The operation is being coordinated by the Intellectual Property Rights Coordination Center and is aimed at tackling decorative and unapproved contact lenses.
Operation Double Vision has seized 20,000 pairs of counterfeit and decorative contact lenses this year.
Officials are warning consumers not to buy contact lenses from Halloween or novelty shops, or online if the seller does not require a prescription.
Homeland Security Investigations executive associate director Peter Edge said: “Make no mistake, contact lenses are medical devices that should be prescribed by trained professionals.”
Jeffrey Hackleman, president of the Georgia Optometric Association, added: "You only get one pair of eyes and risking a lifetime of vision for a quick thrill is quite frankly not being vision smart.”